Mix & Match of Covaxin, Covishield elicits 4 times antibody response, says study

Hyderabad | Tuesday | 4th January, 2022

Summary:

Hyderabad, Jan 4 (PTI) Mixing of COVID-19 vaccines Covaxin and Covishield as first and second doses or vice versa was found to be four times effective, a study by city-based AIG Hospitals along with a team of researchers from the Asian Healthcare Foundation has said.

The study was conducted to determine the safety profile of mixing Covishied and Covaxin along with checking the antibody response, a press release from AIG said on Monday.

The most important finding of the study was that the Spike-protein neutralizing antibodies found in the mixed vaccine groups were significantly higher than the same-vaccine groups, D Nageshwar Reddy, Chairman of AIG Hospitals said.

“Spike-protein neutralizing antibodies are the ones which kill the virus and reduce the overall infectivity.

We found that when the first and second dose are of different vaccines, the Spike-protein antibody response is four times higher compared to two-dose of same vaccine,” Dr.

Reddy who is also among the researchers involved in the study said.